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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SKP2 All Species: 13.64
Human Site: S19 Identified Species: 30
UniProt: Q13309 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13309 NP_005974.2 424 47761 S19 L S S N V A T S F T W G W D S
Chimpanzee Pan troglodytes XP_001147537 379 42771
Rhesus Macaque Macaca mulatta XP_001093834 422 47441 S19 L S S N V A T S F T W G W D S
Dog Lupus familis XP_546346 749 81658 S344 Q S S N V T T S F T W G W D S
Cat Felis silvestris
Mouse Mus musculus Q9Z0Z3 424 47748 S19 Q S G N V T T S F T W G W D S
Rat Rattus norvegicus Q9QZH7 276 30442
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001007983 443 49750 G46 S G S N V S T G F S W D W D S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036659 499 55071 S71 D S P A V E D S L S M S R Q S
Honey Bee Apis mellifera XP_395497 484 54314 K52 S A S K N N T K W S Y S G D A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780472 456 51238 G15 D P G H D R A G V I W D F D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O49286 360 39891
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.3 91.9 52.3 N.A. 86.3 23.5 N.A. N.A. 64.1 N.A. N.A. N.A. 30 27.8 N.A. 31.3
Protein Similarity: 100 89.3 94.5 54.6 N.A. 92.9 36.7 N.A. N.A. 74.4 N.A. N.A. N.A. 50.9 50.6 N.A. 50
P-Site Identity: 100 0 100 86.6 N.A. 80 0 N.A. N.A. 60 N.A. N.A. N.A. 26.6 20 N.A. 13.3
P-Site Similarity: 100 0 100 86.6 N.A. 80 0 N.A. N.A. 73.3 N.A. N.A. N.A. 33.3 53.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 20 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 36 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 10 0 19 10 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 10 0 10 0 0 0 0 19 0 64 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 46 0 0 0 10 0 0 % F
% Gly: 0 10 19 0 0 0 0 19 0 0 0 37 10 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 19 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 46 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 19 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % R
% Ser: 19 46 46 0 0 10 0 46 0 28 0 19 0 0 55 % S
% Thr: 0 0 0 0 0 19 55 0 0 37 0 0 0 0 0 % T
% Val: 0 0 0 0 55 0 0 0 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 55 0 46 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _